The paper present theoretical and experimental studies of the energy dissipation performance of a composite structure composed in a multilayer nano-composite damping coating applied on a tungsten carbide shim and placed beneath the cutting insert.The coated shim placed closed to the cutting zone is subjected to high compressive and shear stresses a
Imbalance of gut microbiota can induce or aggravate intestinal inflammation.To enhance our understanding of the molecular mechanisms of gut microbiota and inflammatory bowel disease (IBD), we studied the role of repulsive guidance molecule b (RGMb) in gut microbiota and colitis in mice.We generated Rgmb knockout mice and inducible Rgmb knockout mic
Number symbols, such as Arabic numerals, are cultural inventions that have transformed human mathematical skills.Although their acquisition is at the core of early elementary education in children, it remains unknown how the neural representations of numerals emerge during that period.It is also unclear whether these relate to an ontogenetically ea
An entirely unelected Upper House looks, at first sight, to sit uneasily with a XXIst century democracy.In this context, the House of Lords has had to carve out its own role in the British constitutional settlement.Since the reforms of the beginning of the XXIst century, its legitimacy and positions 2 Piece Desk have shifted.This article focuses on
Tumor mutation burden (TMB) is a widely recognized stratification biomarker for predicting the efficacy of immunotherapy; however, the number and universal definition of the categorizing thresholds remain debatable due to the multifaceted nature of efficacy and the imprecision of TMB measurements.We proposed a minimal joint p-value criterion from t